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1

Cytochromes P450 and uridine triphosphate-glucuronosyltransferases: Model autoantigens to study drug-induced, virus-induced, and autoimmune liver disease

M P Manns, P Obermayer-Straub

Journal:

Year:

1997

Language:

english

File:

PDF, 279 KB

english, 1997

2

Cytochrome P450 enzymes and UDP-Glucuronosyltransferases as hepatocellular autoantigens

Petra Obermayer-Straub, Michael Peter Manns

Journal:

Molecular Biology Reports

Year:

1996

Language:

english

File:

PDF, 729 KB

english, 1996

3

The genetic background of autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy and its autoimmune disease components

Arndt Vogel, Christian P. Strassburg, Petra Obermayer-Straub, Georg Brabant, Michael P. Manns

Journal:

Journal of Molecular Medicine

Year:

2002

Language:

english

File:

PDF, 127 KB

english, 2002

4

Viral induction of autoimmunity: mechanisms and examples in hepatology

M. P. Manns, P. Obermayer-Straub

Journal:

Journal of Viral Hepatitis

Year:

1997

Language:

english

File:

PDF, 593 KB

english, 1997

5

Autoimmune polyglandular syndrome type 1

Petra Obermayer-Straub, Christian P. Strassburg, Michael P. Manns

Journal:

Clinical Reviews in Allergy & Immunology

Year:

2000

Language:

english

File:

PDF, 281 KB

english, 2000

6

Autoimmunity in liver diseases

Christian P. Strassburg, Petra Obermayer-Straub, Michael P. Manns

Journal:

Clinical Reviews in Allergy & Immunology

Year:

2000

Language:

english

File:

PDF, 160 KB

english, 2000

7

Autoimmune regulator AIRE: Evidence for genetic differences between autoimmune hepatitis and hepatitis as part of the autoimmune polyglandular syndrome type 1

Arndt Vogel, Heike Liermann, Andrea Harms, Christian P. Strassburg, Michael P. Manns, Petra Obermayer-Straub

Journal:

Year:

2001

Language:

english

File:

PDF, 173 KB

english, 2001

8

7 Cytochromes P450 and UDP-glucuronosyltransferases as hepatocellular autoantigens

Petra Obermayer-Straub, Michael P. Manns

Journal:

Baillière's Clinical Gastroenterology

Year:

1996

Language:

english

File:

PDF, 2.35 MB

english, 1996

9

6 Autoimmune polyglandular syndromes

Petra Obermayer-Straub, Michael P. Manns

Journal:

Baillière's Clinical Gastroenterology

Year:

1998

Language:

english

File:

PDF, 3.43 MB

english, 1998

10

Autoimmunity in hepatitis C and D virus infection

C. P. Strassburg, P. Obermayer-Straub, M. P. Manns

Journal:

Journal of Viral Hepatitis

Year:

1996

Language:

english

File:

PDF, 927 KB

english, 1996

11

Distribution and Inducibility by 3-Methylcholanthrene of Family 1 UDP-Glucuronosyltransferases in the Rat Gastrointestinal Tract

Bärbel Grams, Andrea Harms, Sabine Braun, Christian P. Strassburg, Michael P. Manns, Petra Obermayer-Straub

Journal:

Archives of Biochemistry and Biophysics

Year:

2000

Language:

english

File:

PDF, 397 KB

english, 2000

12

Hepatitis C and D, Retroviruses and Autoimmune Manifestations

Petra Obermayer-Straub, Michael P Manns

Journal:

Journal of Autoimmunity

Year:

2001

Language:

english

File:

PDF, 163 KB

english, 2001

13

Autoantibodies in hepatitis delta

T Philipp, P Obermayer-Straub, MP Manns

Journal:

Biomedicine & Pharmacotherapy

Year:

1995

Language:

english

File:

PDF, 632 KB

english, 1995

14

Cytochrome P450 2A6: a new hepatic autoantigen in patients with chronic hepatitis C virus infection

Georgios N Dalekos, Petra Obermayer-Straub, Moritz Bartels, Takashi Maeda, Anne Kayser, Sabine Braun, Stephanie Loges, Eleonore Schmidt, M.Eric Gershwin, Michael P Manns

Journal:

Journal of Hepatology

Year:

2003

Language:

english

File:

PDF, 285 KB

english, 2003

15

Autoantibodies against glucuronosyltransferases differ between viral hepatitis and autoimmune hepatitis

CP Strassburg, P Obermayer-Straub, B Alex, M Durazzo, M Rizzetto, RH Tukey, MP Manns

Journal:

Gastroenterology

Year:

1996

Language:

english

File:

PDF, 476 KB

english, 1996

16

Two cytochromes P450 are major hepatocellular autoantigens in autoimmune polyglandular syndrome type 1

Maria Grazia Clemente, Antonella Meloni, Petra Obermayer-Straub, Fulvia Frau, Michael Peter Manns, Stefano de Virgiliis

Journal:

Gastroenterology

Year:

1998

Language:

english

File:

PDF, 286 KB

english, 1998

17

Antimitochondrial antibodies agaimst dihydrolipoamide acyltransferases (PDC-E2 and BCKADCE2) in immunofluorescent AMA-negative rheumatoid arthritis sera

Janos Kis, Antal Csepregi, C.P. Strassburg, P. Obermayer-Straub, S. Kneip, A. Kayser, E. Nemesanszky, M. Manns

Journal:

Journal of Hepatology

Year:

2002

Language:

english

File:

PDF, 231 KB

english, 2002

18

Differences in the regulation of cytochrome P450 family members during liver regeneration

Christian Trautwein, Tim Rakemann, Petra Obermayer-Straub, Monika Niehof, Michael Peter Manns

Journal:

Journal of Hepatology

Year:

1997

Language:

english

File:

PDF, 845 KB

english, 1997

19

Definition of a novel CYP2D6 epitope in autoimmune hepatitis type 2 and in chronic hepatitis C

P. Obermayer-Straub, T. Sugimura, S. Braun, B. Lüttig, S. Loges, A. Kayser, M. Durazzo, C. Strassburg, M.P. Manns

Journal:

Journal of Hepatology

Year:

1998

Language:

english

File:

PDF, 168 KB

english, 1998

20

LKM autoantibodies in autoimmune hepatitis, APS1 and chronic hepatitis C: quantification of anti-CYP2D6 autoantibodies with 35S-labeled recombinant protein and comparison of target proteins

P. Obermayer-Straub, A. Kayser, S. Braun, S. Loges, B. Lüttig, J. Perheentupa, M.P. Manns

Journal:

Journal of Hepatology

Year:

1998

Language:

english

File:

PDF, 173 KB

english, 1998

21

Hepatic autoantigens in the autoimmune polyglandular syndrome type 1 and autoimmune hepatitis type 2

P. Obermayer-Straub, S. Braun, S. Loges, M.G. Clemente, B. Lüttig, B. Grams, J. Perheentupa, M.P. Manns

Journal:

Journal of Hepatology

Year:

1998

Language:

english

File:

PDF, 160 KB

english, 1998

22

Epitope mapping of cytochrome P4502D6 autoantigen in patients with chronic hepatitis C during α-interferon treatment

Georgios N Dalekos, Heiner Wedemeyer, Petra Obermayer-Straub, Anne Kayser, Ayse Barut, Hannah Frank, Michael P Manns

Journal:

Journal of Hepatology

Year:

1999

Language:

english

File:

PDF, 861 KB

english, 1999

23

Development of cytochrome P450 2D6-specific LKM-autoantibodies following liver transplantation for Wilson's disease - possible association with a steroid-resistant transplant rejection episode

Ansgar W Lohse, Petra Obermayer-Straub, Guido Gerken, Silvia Brunner, Ulrich Altes, Hans Peter Dienes, Michael P Manns, Karl-Hermann Meyer zum Büschenfelde

Journal:

Journal of Hepatology

Year:

1999

Language:

english

File:

PDF, 967 KB

english, 1999

24

Cytochromes P450 and uridine triphosphate-glucuronosyltransferases: Model autoantigens to study drug-induced, virus-induced, and autoimmune liver disease

MP Manns, P Obermayer-Straub

Journal:

Year:

1997

Language:

english

File:

PDF, 291 KB

english, 1997

25

LKM3 autoantibodies in hepatitis C cirrhosis: a further phenomenon of the HCV-induced autoimmunity

Antal Csepregi, Elemér Nemesánszky, Birgit Luettig, Petra Obermayer-Straub, Michael Peter Manns

Journal:

American Journal of Gastroenterology

Year:

2001

Language:

english

File:

PDF, 191 KB

english, 2001

26

Autoimmune hepatitis

Petra Obermayer-Straub, Christian P. Strassburg, Michael P. Manns

Journal:

Journal of Hepatology

Year:

2000

Language:

english

File:

PDF, 2.19 MB

english, 2000

27

Increased incidence of anti-LKM in a consecutive sample of HCV patients from central Greece: A preliminary study

G.N. Dalekos, E. Makri, S. Loges, P. Obermayer-Straub, Th. Tsikrikas, K. Zachou, G. Papadamou, M.P. Manns

Journal:

Journal of Hepatology

Year:

2000

Language:

english

File:

PDF, 112 KB

english, 2000

28

Identification of cyclosporine A and tacrolimus glucuronidation in human liver and the gastrointestinal tract by a differentially expressed UDP-glucuronosyltransferase: UGT2B7

Christian P Strassburg, Ayse Barut, Petra Obermayer-Straub, Qing Li, Nghia Nguyen, Robert H Tukey, Michael P Manns

Journal:

Journal of Hepatology

Year:

2001

Language:

english

File:

PDF, 351 KB

english, 2001

29

Two B-cell autoepitopes are recognized on the human BCKADC-E2 by PBC sera

A. Csepregi, A. Kayser, S. Kneip, P. Obermayer-Straub, C.P. Strassburg, E. Nemesánszky, F. Szalay, M.P. Manns

Journal:

Journal of Hepatology

Year:

2001

Language:

english

File:

PDF, 266 KB

english, 2001

30

Hepatic Autoantigens in Patients With Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy

Petra Obermayer-Straub, Jaakko Perheentupa, Sabine Braun, Anne Kayser, Ayse Barut, Stefanie Loges, Andrea Harms, Georgios Dalekos, Christian P. Strassburg, Michael P. Manns

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 311 KB

english, 2001

31

Identification of tissue specific cyclosporine a and tacrolimus glucuronidation in the human gastrointestinal tract by a differentially expressed UDP-glucuronosyltransferase: UGT2B7

Strassburg, Christian P., Topp, Juliane, Barut, Ayse, Obermayer-Straub, Petra, Li, Qing, Nguyen, Nghia, Tukey, Robert H., Manns, Michael P.

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 172 KB

english, 2000

32

Autoepitopes on UDP-glucuronosyl transferases (LKM-3) in autoimmune hepatitis differ from those in hepatitis D

Strassburg, C.P., Obermayer-Straub, P., Alex, B., Philipp, T., Tukey, R., Manns, M.P.

Journal:

Gastroenterology

Year:

1995

Language:

english

File:

PDF, 158 KB

english, 1995

33

LKM3 autoantibodies in hepatitis C cirrhosis: a further phenomenon of the HCV-induced autoimmunity

Csepregi, Antal, Nemesanszky, Elemer, Luettig, Birgit, Obermayer-Straub, Petra, Manns, Michael Peter

Journal:

American Journal of Gastroenterology

Year:

2001

Language:

english

File:

PDF, 191 KB

english, 2001

34

Cytochrome P450 1A2 Is a Hepatic Autoantigen in Autoimmune Polyglandular Syndrome Type 1 1

Clemente, Maria Grazia, Obermayer-Straub, Petra, Meloni, Antonella, Strassburg, Christian P., Arangino, Vincenzo, Tukey, Robert H., De Virgiliis, Stefano, Manns, Michael P.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1997

Language:

english

File:

PDF, 7.38 MB

english, 1997

35

A Major CYP2D6 Autoepitope in Autoimmune Hepatitis Type 2 and Chronic Hepatitis C is a Three-dimensional Structure Homologous to Other Cytochrome P450 Autoantigens

Sugimura, T., Obermayer-Straub, P., Kayser, A., Braun, S., Loges, S., Alex, B., Lüttig, B., Johnson, E.F., Manns, Michael P., Strassburg, Christian P.

Journal:

Year:

2002

Language:

english

File:

PDF, 613 KB

english, 2002

36

Increased incidence of anti-LKM autoantibodies in a consecutive cohort of hepatitis C patients from central Greece

Dalekos, Georgios N., Makri, Eirini, Loges, Stephanie, Obermayer-Straub, Petra, Zachou, Kalliopi, Tsikrikas, Thomas, Schmidt, Elenore, Papadamou, Georgia, Manns, Michael P.

Journal:

European Journal of Gastroenterology & Hepatology

Year:

2002

Language:

english

File:

PDF, 263 KB

english, 2002

37

Target Proteins in Human Autoimmunity: Cytochromes P450 and Udp-Glycoronosyltransferases

Obermayer-Straub, Petra, Strassburg, Christian Peer, Manns, Michael Peter

Journal:

Canadian journal of gastroenterology

Year:

2000

File:

PDF, 1.39 MB

2000

38

Characterization of a Lipoyl Domain-Independent B-Cell Autoepitope on the Human Branched-Chain Acyltransferase in Primary Biliary Cirrhosis and Overlap Syndrome with Autoimmune Hepatitis

Csepregi, Antal, Obermayer-Straub, Petra, Kneip, Susanne, Kayser, Anne, Loges, Stephanie, Schmidt, Eleonore, Nemesánszky, Elemér, Szalay, Ferenc, Manns, Michael P., Strassburg, Christian P.

Journal:

Clinical & Developmental Immunology

Year:

2003

Language:

english

File:

PDF, 1.25 MB

english, 2003

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